FPGEE Practice Questions

Structure-activity studies of cholinergic drugs indicate that:

I maximum activity is achieved when the quaternary nitrogen is three carbons removed from the ester oxo group.

II structures which display a quasi-ring conformation exhibit muscarinic activity.

III one methyl group of the trimethylammonium group can be replaced by an ethyl group with only slight loss of activity.

The level of which drug should be adjusted during treatment with allopurinol

I- Mercapturic acid

II- Theophillin

III- Anticoagulants

Best drug used in the prevention of exercise-induced asthma may include:

True statements regarding the use of monoclonal antibodies include which of the following?

I Flu-like symptoms commonly occur at the start of therapy.

II T cells are blocked from initiating the rejection process.

III Orthoclone is a human immunoglobulin product.

The above structures are related to one another as:

Osteoporosis is a disease characterized by loss of bone mass and may be aggravated by:

I-Corticosteroids

II-Menopausa

III-Grave’s disease

Importance of Vitamin D in osteoporosis:

I- Increase the absorption of calcium from the small intestine

II- The best vitamin D analog to treat osteoporosis is calcitriol

III- Antacids containing aluminum and magnesium may interfere with proper activity of vitamin

D.  

The ethical principle of veracity requires that:

All are correct concerning the action of corticosteroids in asthma status, EXCEPT:

Once daily dosing of aminoglycosides is effective due to: