Foreign Pharmacy Graduate Equivalency Examination
Last Update 4 days ago
Total Questions : 426
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Drugs used in the treatment of meningitis are all of the following, EXCEPT:
Examples of very narrow spectrum penicillins include all of the following, EXCEPT:
Mechanism of inhibit protein synthesis is characteristic of all the following antibiotics, EXCEPT:
All of the following are narrow spectrum protein synthesis inhibitors, EXCEPT:
Otitis media is an ear infection normally caused by S. pneumoniae and may be best treated by:
Which of the following agents may interfere with the regular effect of penicillins?
In an adequately powered, randomized controlled trial conducted over 3 years, a specific serious side effect (i.e. reduction in leukocytes) with conventional therapy is seen in 0.5% of the study sample. In patients who receive a newly discovered drug, only 0.45% experience the same side effect. Based on these results, the minimum number of patients that would have to receive the new drug for 3 years to statistically demonstrate the prevention of one episode of this side effect in at least one patient is:
Structure-activity studies of cholinergic drugs indicate that:
I maximum activity is achieved when the quaternary nitrogen is three carbons removed from the ester oxo group.
II structures which display a quasi-ring conformation exhibit muscarinic activity.
III one methyl group of the trimethylammonium group can be replaced by an ethyl group with only slight loss of activity.
The level of which drug should be adjusted during treatment with allopurinol
I- Mercapturic acid
II- Theophillin
III- Anticoagulants
True statements regarding the use of monoclonal antibodies include which of the following?
I Flu-like symptoms commonly occur at the start of therapy.
II T cells are blocked from initiating the rejection process.
III Orthoclone is a human immunoglobulin product.
Osteoporosis is a disease characterized by loss of bone mass and may be aggravated by:
I-Corticosteroids
II-Menopausa
III-Grave’s disease
Importance of Vitamin D in osteoporosis:
I- Increase the absorption of calcium from the small intestine
II- The best vitamin D analog to treat osteoporosis is calcitriol
III- Antacids containing aluminum and magnesium may interfere with proper activity of vitamin
D.
All are correct concerning the action of corticosteroids in asthma status, EXCEPT:
Patient has a relevant increase in his asthma symptoms due to environmental allergies. He is currently having salbutamol and fluticasone inhalers. What would you advise as an adjunct medication to treat his symptoms?
Physicochemical factors affecting the rate and extent of percutaneous drug absorption include:
I the partition coefficient of the drug molecule
II the presence of surfactants in the formulation
III the type of ointment base
Which of the following Cytochrome P450 isozymes is responsible for the bulk of phase I metabolism?
In which of the following organs or tissues is the action of acetylcholine NOT described as "nicotinic"?
I Motor endplates of skeletal muscle
II Celiac ganglia
III Circular muscles of the iris
Vitamin that requires an intrinsic factor to be carried out to ileum in order to suffer absorption from the small intestine:
All of the following statements are true regarding chronic inflammation, EXCEPT:
Which of the following reactions is controlled by the pancreatic hormone INSULIN?
Catabolism of carbohydrates is a process characterized by:
I- Consume of energy
II- Release stored energy from carbohydrates
III-Glycogenolysis is an example of carbohydrates catabolism reaction
TESTED 19 May 2024
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